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In recent years, SLC7A11 has attracted increasing attention due to its critical role in the synthesis of GSH, which functions to prevent lipid peroxidation and protect cells from ferroptosis [30]
[DOI] [PMC free article] [PubMed] [Google Scholar] 205.Lawson K
Notably, several uremic solutes have also been implicated in systemic endothelial dysfunction and microvascular injury, suggesting a link to the proteinuriarelated cerebrovascular changes observed in epidemiological PD studies [145]
30) (where R + is the protonated pyridine form of the intermediate and R is a quinonoid intermediate)
