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In the early 1980s, several lines of evidence from Etienne, Baulieu, and Robel (69) challenged the central dogma that neuroactive steroids were exclusively synthesized peripherally, demonstrating for the first time that steroids could be synthesized from cholesterol within the CNS

The Role of Neurosteroids in Memory Deficits Associated With Schizophrenia The cognitive deficits associated with schizophrenia are caused by multiple factors, and elucidating a single causative part of the cognitive component would provide some hope for understanding memory and a basis for therapeutic discovery

Journal of Orthopaedic Research, 24(5), 1109-1117