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Finally, there is no evidence in humans that exogenous lipoic acid can be 'activated' with ATP or GTP and incorporated into lipoic acid-dependent enzymes by a lipoyl transferase (14)

A Y-shaped microfluidic device to study the combined effect of wall shear stress and ATP signals on intracellular calcium dynamics in vascular endothelial cells

The identification of distinct relapse patterns emphasizes that improved methods (including single-cell multi-omics as discussed below) tracking the complex evolutionary history of AML within individual patients are inevitable in the design of further clinical trials as an attempt to overcome LSC-mediated therapy resistance and relapse