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Tumor-associated tertiary lymphoid structures: gene-expression profiling and their bioengineering
The ratio of GSSG to GSH is used as a marker of redox thiol status and oxidative stress
Intriguingly, NADPH-dependent reductive stress stimulated glutaminolysis to generate -KG, which was then converted to succinyl-CoA by oxidative decarboxylation in the TCA cycle or to citrate via IDH2-mediated reductive carboxylation (23)
& Tirosh, B
