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Description
The gut microbiota and its metabolites play a pivotal role in high-altitude adaptation by modulating the host immune system through multiple mechanisms ( 3.2.1 Mitigation of oxidative stress Certain gut microbiota and their metabolites enhance the defense of the gut mucosal barrier by alleviating excessive oxidative stress
Chronic Disease: As part of managing chronic conditions

whole bowel irrigation can be performed by administering 2 L of polyethylene glycol orally every hour (25 mL/kg/hr in children) until the rectal effluent is clear

10.1038/ncb3053 Nat
