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observed elevated TMAO levels in CKD patients who underwent cardiovascular surgery ( n = 227) [47]

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For genetically predicted acetyl-carnitine, we also found an association with higher triglycerides (0.06, 95% CI 0.04 to 0.07) and lower HDL-cholesterol ( 0.03, 95% CI 0.05 to 0.02) (Additional file 2: Fig