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Highlighting the specificity of TGM1, involucrin contains 39 repeats of a 10 amino acid sequence, with each containing three glutamine residues (Eckert and Green, 1986), but only one glutamine residue within this 585-amino acid proteinin the sequence ELPEQ Q VGQP (reactive Q is in bold)is reactive in vitro unless the protein is proteolytically degraded (Simon and Green, 1988)

Individual response may vary

Eur J Pharmacol 701:203212 Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH (2011) The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration

Matrix metalloproteinases: they're not just for matrix anymore