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The receptors for activated Ckinases anchor proteins bind directly with the C2 domain of activated PKC but this has only been shown for PKC II and PKC .141, 142 There are other proteins described as forming proteinprotein interactions with PKC be it adapter proteins, anchor proteins or PKC substrates and these have great potential for therapeutic target development (reviewed in ref

For references and more information , see the section on cardiovascular disease in the Coffee article

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