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PACCs are large, multinucleated cells that are thought to help mediate resistance and metastasis and are generated usually by a stressor, such as chemotherapy or hypoxia (Illidge et al., 2000
Laugier-Hunziker syndrome: a rare cause of mucocutaneous pigmentation
Clin Physiol 1984;4(4):363-365
However, the third nucleotide of this and surrounding codons shows higher genetic flexibility, indicating that the amino acid rather than the nucleotide sequence is critical at this position of the genome
