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5.2 The chronic accumulation of ROS creates a microenvironment conducive to the formation of PCa Chronic inflammation is a significant factor influencing the occurrence and progression of PCa to advanced metastatic disease

Cell viability assay for PDX-derived 3D cell cultures Ex vivo evaluation of cell viability in response to IACS-010759 exposure was performed in HBCx-137 derived cell cultures, following a protocol detailed elsewhere 62

Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor model
