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Additionally, COJEC alone triggered an increase in expression of the ferroptosis inhibitor HSPB1 in LU-NB-1 (Fig

Moreover, animal models (131) and tissue specimens obtained from patients with sarcoidosis (132) showed that hyperproduction of Th2 cytokines is accompanied by tissue macrophage activation and differentiation toward the M2 phenotype, which contributes to the development and maintenance of tissue foci of chronic inflammation, the formation of granulomas, and foci of fibrosis

Clinical trial number Not applicable Graphical Abstract Similar content being viewed by others Introduction Autism spectrum disorder (ASD) is a multifactorial neurodevelopmental condition characterized by a broad spectrum of symptoms, including impairments in social interaction and communication, alongside restricted, repetitive patterns of behavior, interests, or activities [1, 2]