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No tolerance development or suppressive effects on natural healing processes have been observed in research

Anesthesiology 116:924 Del Carpio-Orantes L, Elizalde- Bernal RJJ, Villegas-Dominguez JE, Morales-Ocon JE, Tejero-Da Silveira RK (2017) Pink urine syndrome

Fluoxetine affects embryonic morphogenesis by inhibiting the activity of the Wnt signaling pathway and reducing cell proliferation, and activation of the Wnt signaling pathway partially mitigates the adverse effects of fluoxetine on embryonic morphology through a mechanism of action that is not directly related to the inhibition of serotonin reuptake in the synapse
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doi: 10.1210/en.2010-0981 [DOI] [PubMed] [Google Scholar] 66
