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[7] reported a tethering function of E peptides that could aid in maintaining concentrations of IGF-1 at their site of synthesis to enable more localized effects

JAMA 294 , 15051510 (2005)

While structurally distinct from GLP-1 analogs, GLP-3 R is being investigated for its potential interactions with GLP receptor pathways and its role in energy balance, insulin sensitivity, and weight management
