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J Trace Elem Med Biol 54:6978 Carrillo-Martinez EJ, Flores-Hernndez FY, Salazar-Montes AM, Nario-Chaidez HF, Hernndez-Ortega LD (2024) Quercetin, a flavonoid with great pharmacological capacity

Results Identification of HK2 as a suppressor of TNF-induced cell death mediated by RIPK1 In our previous screening 4 , which is aimed to investigate the role of metabolic pathways in TNF-induced cell death, we found that knockdown of Hk2 sensitized primary hepatocytes to cell death induced by TNF and cycloheximide (CHX), a combination known to induce caspase 8-mediated apoptosis and independent of RIPK1 kinase activity 41

[DOI] [PubMed] [Google Scholar] Boland C

Typical pathological signs include liver disease and pancreatic -cell failure
