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This discrepancy may arise because TEM directly assesses the physical size of air-dried exosomes, while the zetasizer determines their hydrodynamic diameter, which includes the influence of the surrounding liquid layer causing the observed slight increase in particle size [35]

However, excessive ROS production can lead to a vicious cycle of oxidative stress, creating further damage to ETC components which can propagate more electron leakage and ROS production (Zhao et al., 2019)

Jain S, Baer RJ, McCulloch CE, Rogers E, Rand L, Jelliffe-Pawlowski L, et al

Furthermore, the authors reported a 72% reduction in snoring and a decrease in the Epworth Sleepiness Scale (ESS) score from 14.8 3.5 to 8.2 4.1