glutathione s transferase rhamnetin transferases as mediators of signaling pathways involved in cell proliferation and cell death Regulation of Glutathione S-Transferase Omega

Buljat, G

If we go back to first principles and foundational biochemistry, we definitely want to support glutathione production, via its precursor amino acids: cysteine, glycine, and glutamate, and the biochemical pathways and cofactors involved in its production (e.g., methylation cycle, B vitamins especially B2, B3, B6, B9,and B12)

Golldack D, Lking I, Yang O (2011) Plant tolerance to drought and salinity: stress regulating transcription factors and their functional significance in the cellular transcriptional network

Since no appropriate PR3-AAV model exists, clinical studies with adjunctive DPP1 inhibitor administration in patients with PR3-AAV may provide the best approach to test this hypothesis