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Humanized gnotobiotic mouse experiments C57BL/6JNarl male germ-free mice (812 weeks of age) were used to establish four study groups of hGM model through fecal microbiota transplantation (FMT) from donors of two OCCT-defined high-TMAO producers (O15 and O32) and two OCCT-defined low-TMAO producers (V12 and V25)

Debido a su magnitud y trascendencia, la obesidad es considerada en Mxico como un problema de Salud Pblica, como lo demuestra lo reportado por la Encuesta Nacional de Salud del ao 2000, detectando que desde edades tempranas existe una elevada prevalencia de sobrepeso y obesidad, ya que en los adolescentes se encuentra un 29% de sobrepeso y obesidad y, en lo referente a los adultos, en mujeres de 20-59 aos se obtuvo un 36.1% de sobrepeso y 28.1% de obesidad y, en hombres del mismo grupo, 40.9% de sobrepeso y 18.6% de obesidad

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