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doi: 10.1016/j.mam.2012.12.002
For example, stir-frying Strychni Semen at 230240 for 34 min breaks ether bonds in strychnine and brucine, forming isomers and N-oxides with lower toxicity approximately 1/10 to 1/15 of the original compounds, while retaining pharmacological effects [144]

PMID 39325560

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