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This does not mean AOD 9604 does not work

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However, when comparing the reductive half-reaction of the C31S variant (Figure 6) to that of the U597C enzyme it is immediately apparent that, although the reduction of this disulfide is proposed to be necessary for the reduction of GSSG, this process is not captured in the transient state kinetic data presented

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doi: 10.1016/j.jhep.2018.06.008 15 KazankovKJrgensenSMDThomsenKLMllerHJVilstrupHGeorgeJet al

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However, the capacity of shrimp to catabolize lipids may be exceeded, leading to lipid accumulation and metabolic stress

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