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The most relevant DNA repair pathways responsible for repair cisplatin-induced DNA damage are nucleotide excision repair (NER) and homologous recombination (HR)

Bioactivity of Pyrrolo [1, 2-a] pyrazine-1, 4-dione, hexahydro-3-(phenylmethyl)-Extracted from Streptomyces sp

Administration of radio-labeled proteins, such as insulin-like growth factor-1 (IGF-1) and interferon-beta 1b (IFN-1b), into the rat nose leads to their distribution along trigeminal and olfactory nerve associated pathways and dissemination into both rostral and caudal regions of the rat brain within 3060 min, thus providing evidence of rapid brain access of CNS acting drugs through intranasal delivery [32, 33]

[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Huang X., Motea E.A., Moore Z.R., Yao J., Dong Y., Chakrabarti G., Kilgore J.A., Silvers M.A., Patidar P.L., Cholka A., et al
