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Half-Life: AOD 9604 2 mg has a relatively short half-life, typically estimated to be around 2-3 hours

however, they also highlight challenges such as inconsistent degradation rates, potential toxicity, and a paucity of clinical evidence

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In particular: NICE Technology Appraisal TA875 provides a positive recommendation for semaglutide (Wegovy) for chronic weight management in adults meeting specific criteria (BMI 35 kg/m with at least one weight-related comorbidity, or BMI 3034.9 kg/m in certain circumstances), when used within a specialist weight management service
