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Recent research shows berberine can cross the BBB to some extent and that nanoformulations or coadministration with absorption enhancers can raise its brain levels [44]

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& Naba, A

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Arylamine N-acetyltransferase acetylation polymorphisms: Paradigm for pharmacogenomic-guided therapy-A focused review

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isoelectric points and size [3], and those that use selective endogenous or engineered [4] protein affinity

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