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Remarkably, one double-blind randomised trial found that both 20 g/mL and 40 g/mL doses effectively reduced pain without significant differences between concentrations, suggesting a threshold effect where lower doses sufficiently activate therapeutic pathways
However, in modern times we are constantly exposed to toxins and stress, continuously upsetting our system, never enabling inflammation to truly disappear
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
doi: 10.1016/0014-5793(80)80299-7
