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18 Mitochondrial dysfunction resulting from oxidative stress is one possible mechanism contributing to the progressive degeneration in people with MS and underlying fatigue
Three distinct pathways including succinate pathway, acrylate pathway, and propanodiol pathway, can generate propionic acid (Reichardt et al., 2014)
moreover, it is crucial for cell survival, which compromises plasma membrane, DNA and mitochondrial integrity, and eventually leads to the apoptosis
