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This product is supplied as a high-purity research compound and is manufactured to meet stringent quality standards, including LPS-free and endotoxin-free specifications

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10.1093/ajcn/nqy072 [DOI] [PubMed] 33.Sezer RG, Akolu HA, Bozaykut A, zdemir GN (2018) Comparison of the efficacy of parenteral and oral treatment for nutritional vitamin B12 deficiency in children

The dosing framework comes from extrapolation: murine studies scaled by body surface area, in vitro keratinocyte studies reverse-engineered to estimate required serum concentration, and anecdotal protocols from research communities using off-label peptides