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Description
We have recently demonstrated that the epicardium undergoes epithelial-mesenchymal-transition in a Wnt dependent manner after cardiac injury and generates cardiac fibroblasts that reside in the subepicardial space and contribute to cardiac fibrosis

Hyperoxaluria develops in 5% of patients taking large doses
Science 353 , 664669 (2016)
Overlay plot showing optimized box Behnken experimental design conditions as a flag within the design space is illustrated in Figure 3
