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Fish meal is a byproduct of fish processing, so they are not removing fish from the ocean just for the purpose of making fish oil
Gastroenterol, 117: 942-952, 1999

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Therefore, by blocking the NLS of the PFKFB3 protein, the intranuclear translocation of PFKFB3 can be prevented, thereby increasing its intracytoplasmic content and enhancing cellular glycolysis (45)