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While the peptide appeared well tolerated in these trials, the absence of reproducible clinical benefit meant the molecule did not progress to approval or further late-stage studies
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All animal procedures carried out in this study were reviewed, approved and supervised by the Institutional Animal Care and Use Committee of the Ethics Committee of Xi'an Jiaotong University Health Science Center, China
Naltrexone as a once daily medication may offer benefits for those who have problems with adherence to medications that require 3 times daily dosing
