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132 A randomized placebo-controlled trial in 24 men with high cholesterol levels found 25 mg of DHEA daily for 12 weeks improved blood vessel function, lowered blood glucose levels, and reduced levels of a marker of thrombosis (blood clot) risk

doi: 10.1186/s40478-020-0894-0

To estimate CYP activities in the S9-fractions, 183 L of PBS (final composition: 10 mM disodium hydrogen phosphate, 1.8 mM potassium dihydrogen phosphate, 137 mM sodium chloride, 2.7 mM potassium chloride, 5 mM magnesium chloride

In this sense, the relationship between the binding properties of a drug and its active form, as well as its membrane location, deserves attention