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These enzyme families create a vital "PARP-NAD-SIRT axis" that supports DNA repair
PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
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Though anecdotal reports are common, large-scale human trials remain limited, highlighting the need for further scientific validation
