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That basically arms the body by giving a sufficient amount of information to an immune cell saying, if you see a cell thats infected with the virus, just go and destroy that. For some, efficacy might not be the most important metric in choosing a booster, Dionne adds

Calves (up to 1 year): 1mL/50 kg Cattle (1-2 years): 1mL/75 kg Cattle (over 2 years): 1mL/100kg Cows: 3 4 weeks before calving, mating and drying off Calves: At day 1 and weaning Heifers: Every 3 months, especially 3 4 weeks before mating Additional: Every 2 months in wet conditions WITHHOLDING PERIODS No withholding period is required when used as directed

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Repeated freezethaw cycles should be avoided, as they accelerate degradation