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Our observed complex structure differs fundamentally from all previously published models of the hTrxR1hTrx1 complex and provides new insights into the catalytic mechanism of large, eukaryotic TrxRs
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We identified a natural killer (NK) cell cluster that expressed Nkg7 , Gzma , Klra4 and Klre1 but, importantly, did not express T cell markers (Extended Data Fig
This lactate-NADH antioxidant mechanism operates in concert with the GSH system, collectively maintaining neuronal redox balance under conditions of activation or metabolic stress
