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Currently, ProTide technology has extensive applications in drug discovery and design

The phenotype of patients with genetic defects in IGF-I is characterized by intrauterine and postnatal growth failure, microcephaly, possible deafness, and developmental delay

They possess a high synthetic capacity for GSH due to high expression of (GCL) and cystine/glutamate antiporter (xCT), and can export GSH to neighboring neurons and glia

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