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In ageing murine hoststhe demographic most prone to immunosenescenceseven-day supplementation (10 mg kg -1 , i.p.) doubles splenic NK-cell numbers, boosts CD107a degranulation and elevates IFN- release via a JAK3STAT5T-bet relay ( + N1 neutrophils, augments neutrophil extracellular-trap formation and curbs metastatic seeding, highlighting a granulocytic dimension to its onco-immunology profile ( low CXCR2 + TNF- high effectors that promote tumour lysis, whereas N2 counterparts are Arg-1 high VEGF-A high cells that foster angiogenesis and immunosuppression

BAT is increasingly recognized as a powerful metabolic target, playing a significant role in regulating body composition and energy expenditure

[DOI] [PubMed] [Google Scholar] [13].Graner E, Tang D, Rossi S, Baron A, Migita T, Weinstein LJ, et al