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DNA damage activates PARPs that can use up to 90% of the cell's NAD+, which makes DNA repair heavily reliant on NAD+ availability
[DOI] [PubMed] [Google Scholar] 51.Minegishi Y, Tsukino H, Muto M, Goto K, Gemma A, Tsugane S, Kudoh S, Nishiwaki Y, Esumi H

& Jeong, S

With the 5mg/ml concentration, a 1.25mg dose equals 25 units
