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Although the cytotoxicity of TOP1 inhibitors is slightly lower than that of DNA-damaging agents, an optimized linker design achieves a higher DAR with better stability, enhancing the bystander effect
10.2174/1568009618666181003170027 366 YouZ.ZhangS.ShenS.YangJ.DingW.YangL.et al (2018)
2021 (Scientific Reports) Proteomic profiles identified response pathways tied to inflammation and tissue-remodeling modulation in HIV-NAFLD
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