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We show that some of the most recent findings regarding the influence of pH on renal pathophysiology and metabolism relate to central topics of investigation from the end of the XIX century and most of the XX century, but with a shift in focus towards the pro-inflammatory arm of the disease, they were somehow left in the backseat in the few past decades

Kidney stones can disrupt urine outflow, leading to increased intrarenal pressure, impaired GFR, and elevated BUN concentrations in EG-exposed rats 50

Although considerable effort has been devoted to this field, a signal long-term effective therapy has not been identified

BPC-157 is classified as a gastric pentadecapeptide and is notable for its stability in acidic conditions and high water solubility, properties that are uncommon among peptides of similar size