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Ferroptosis, an iron-dependent form of regulated cell death, has emerged as a promising avenue for glioblastoma therapy

Proksch E (2018) pH in nature, humans and skin

doi: 10.1016/j.xcrm.2025.102259
The core mechanisms include decreased expression of HMGCS2 (a key enzyme in ketone body synthesis), insufficient substrates due to impaired fatty acid -oxidation, abnormal MQC, and disrupted PPAR regulatory pathways (Moore et al., 2022
