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After removing detached cells by PBS washing, wounded cells were treated with 100 L of medium containing one of the following experimental conditions: SG (CTR), HG, HG supplemented with Epitalon at different concentrations (20, 40, or 60 ng/mL) or mannitol

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Hypoxia is able to regulate glycolysis, glycogen synthesis, lipid metabolism and oxidative phosphorylation, thus playing a vital role in tumor cell survival and growth during all stages of metastasis (247)
