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In September 2024, however, the regulators Gastrointestinal Drugs Advisory Committee nearly unanimously voted against the oral drug, noting that Intercept had not provided enough data to support Ocalivas clinical benefit

The short half-life generally results from rapid renal clearance, enzymatic digestion by proteases, or both [1]

doi: 10.1186/s12967-020-02374-0 10 MeizlishMLPineABBishaiJDGoshuaGNadelmannERSimonovMet al
