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While this phenomenon is under investigation, without being bound to a particular theory, it is believed that ALPPL2 exists as a stable dimer on the cell surface (a common property of the AP family), but less so in solution due to lack of membrane association that stabilizes the otherwise weak monomer- monomer interaction, which leads to an avidity -based preferential binding by our antibody to membrane ALPPL2

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R., McGrath, D

Combining compounds that act through different pathways NAD preservation and mitochondrial efficiency for 5-Amino-1MQ, direct fat cell modulation for AOD-9604 can create a more robust fat-loss environment than using either alone