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Furthermore, iHLOs enable patient-specific modeling, providing a platform for precision medicine tailored to individual genetic and pathological conditions 12,13

For peak assignment, 2D NMR homonuclear total correlation (TOCSY) and heteronuclear single-quantum correlation (HSQC) spectra were acquired for selected samples, along with comparison with existing literature and spectral databases, such as Bruker BIOREFCODE (AMIX-viewer 3.9.14, Bruker Biospin, Rheinstetten, Germany), human metabolome database (HMDB) [34] and Chenomx NMR Suite (Chenomx Inc, Edmonton, AB, Canada)

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Fortunately for those who require B12 by injection, when part of our medical weight loss program, Dr