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FIGURE 3 Due to lack of oxygen, hypoxia leads to inhibition of prolyl hydroxylase, which is also referred as prolyl hydroxylase domain (PHD) protein

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While at pH value greater than 6.5, the decrease might be due increased ionization of GSH which made the non-enzymatic rate product formation much rapid to upset the enzymatic rate

Another study found that EGCG has strong neuroprotective effects on PD mice and human neuroblastoma cells
