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Increased urinary type IV collagen marks the development of glomerular pathology in diabetic d/db mice

Patients with reduced corneal nerve fiber density showed significant increases in nerve fiber density compared with no change in the placebo group

10.1136/jcp.49.7.560 55

This upregulation of VEGF was accompanied by the formation of angiogenic factors, highlighting the intricate interplay between vascular remodeling and neuroinflammation in EAE pathology
