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Many autistic individuals struggle with loud or unpredictable noise
Two isozymes of heme oxygenase play distinct role: HMOX1 , an inducible enzyme regulated by oxidative stress and transcription factors like NRF2 , and HMOX2 , a constitutively expressed form involved in normal cellular homeostasis [16]

K., van den Wijngaard, R

Nature 448 , 7377 (2007)
