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Curcumin can act as a blood thinner or an anticoagulant, so its best to avoid it or discuss it with your doctor if you have a bleeding disorder or youre already taking another blood thinner

Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers

Or you could be deficient in Vitamin B12, which results in decreased energy and burning fewer calories
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