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However, TRT has contraindications and side effects that cannot be ignored

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Furthermore, NO enhances the migration of epithelial cells and fibroblasts both in vitro and in animals [69, 70]

This effect was likely due to attenuation of spinogenesis promoted by HGF and Dihexa treatments since, without the antagonizing effect of Hinge, each agonist increased mini-AMPA frequencies (Figure 13 A-B and Figure 10) thus forming functional synaptic connections
