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Although as you have mentioned, you are stage 0 and your risk of relapse, with or without therapy, is quite low

Furthermore, studies have found that HDAC (histone deacetylase), epigenetic regulators that remove acetyl groups from histones, are closely associated with endothelial dysfunction, inflammation, and myocardial fibrosis through their epigenetic regulatory actions (Jin et al., 2017a)

Moreover, ROS influence androgen metabolism by inhibiting sulfotransferase (SULT) enzymes, which normally sulfate and inactivate androgens, thereby increasing the levels of bioactive androgens

doi: 10.1038/s41420-024-02168-z 187