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[DOI] [PubMed] [Google Scholar] 168.Tannous, A., Pisoni, G

For patients who experience severe "histamine dumps" at night, which can cause insomnia, sudden tachycardia, or night sweats, taking the dose in the late afternoon or early evening may provide targeted mast cell stabilization during the most vulnerable hours

Supporting normal detoxification pathways

The following immunosuppressive agents may be considered as well: tacrolimus, mycophenolate mofetil and thalidomide
