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These findings provide robust evidence supporting the role of ferroptosis in chondrocyte death within the context of ROSassociated OA pathogenesis [51]
up to 70% of fALS cases are majorly attributed to four genes: C9orf72, SOD1, TARDBP, and FUS (29), while other ALS-causing genes and their roles are enlisted in Table 2
Effect of conditioned media on nerve cell differentiation
To further clarify these relationships, future studies integrating metallomic data with bio-clinical parameters such as cytokine levels, immune cell phenotypes, and epigenetic modifications will be essential
